Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.33 |
| ▸ | RHOC | P08134 | 2/20 | 0.33 |
| ▸ | RHOA | P61586 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979247 | 0.97 | HTT (0.38) | HTTCACNA1BRHOCRHOAHDAC1 | |
| SCHEMBL8659999 | 0.89 | HTT (0.37) | HTTCACNA1BRHOCRHOAKDM4E | |
| SCHEMBL8629077 | 0.88 | SCN8A (0.40) | HTTCACNA1BRHOCRHOAKDM4E | |
| SCHEMBL7975920 | 0.86 | HTT (0.40) | HTTCACNA1BRHOCRHOAHDAC1 | |
| SCHEMBL8408424 | 0.86 | HTT (0.38) | HTTCACNA1BRHOCRHOASIGMAR1 | |
| SCHEMBL7977795 | 0.85 | RHOC (0.45) | RHOCRHOAHDAC1SIGMAR1TBK1 | |
| SCHEMBL7982119 | 0.85 | HTT (0.34) | HTTCACNA1BRHOCRHOASIGMAR1 | |
| SCHEMBL7979566 | 0.85 | SCN8A (0.43) | HTTCACNA1BRHOCRHOACYP3A4 | |
| SCHEMBL7976122 | 0.85 | HTT (0.36) | HTTCACNA1BRHOCRHOAKDM4E | |
| SCHEMBL7979320 | 0.83 | HTT (0.37) | HTTCACNA1BRHOCRHOASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0824514-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-02-25 | — | — | EP | disclosed |