Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.34 |
| ▸ | RHOC | P08134 | 3/20 | 0.34 |
| ▸ | RHOA | P61586 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977794 | 0.97 | HTT (0.37) | HTTSCN8ARHOCRHOAPPARG | |
| SCHEMBL8408424 | 0.89 | HTT (0.38) | HTTSCN8ARHOCRHOAPPARG | |
| SCHEMBL7979566 | 0.88 | SCN8A (0.43) | HTTSCN8ARHOCRHOAPPARG | |
| SCHEMBL7976269 | 0.86 | HTT (0.40) | HTTSCN8ARHOCRHOAPPARG | |
| SCHEMBL8659999 | 0.86 | HTT (0.37) | HTTSCN8ARHOCRHOACACNA1B | |
| SCHEMBL7965854 | 0.85 | HTT (0.35) | HTTSCN8ARHOCRHOACACNA1B | |
| SCHEMBL7979250 | 0.85 | RHOC (0.48) | RHOCRHOASIGMAR1MAPTTBK1 | |
| SCHEMBL8629077 | 0.85 | SCN8A (0.40) | HTTSCN8ARHOCRHOAPPARG | |
| SCHEMBL7979390 | 0.84 | SCN8A (0.38) | HTTSCN8ARHOCRHOAPPARG | |
| SCHEMBL7975920 | 0.83 | HTT (0.40) | HTTSCN8ARHOCRHOAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0824514-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-02-25 | — | — | EP | disclosed |