Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763126 | 0.88 | KDM4E (0.58) | KDM4EHPGDALDH1A1GAAMEN1 | |
| SCHEMBL14705882 | 0.87 | HAO2 (0.44) | KDM4EHPGDSMN1; SMN2PIN1ALPL | |
| SCHEMBL7995185 | 0.82 | ALDH1A1 (0.51) | KDM4EHPGDALDH1A1GAAMEN1 | |
| SCHEMBL20376630 | 0.82 | KDM4E (0.47) | KDM4EHPGDALDH1A1GAAMEN1 | |
| SCHEMBL7978027 | 0.81 | KDM4E (0.67) | KDM4EHPGDALDH1A1GAAMEN1 | |
| SCHEMBL7995189 | 0.81 | KDM4E (0.43) | KDM4EHPGDALDH1A1GAAMEN1 | |
| SCHEMBL14705953 | 0.80 | ESR1 (0.46) | KDM4EHPGDALDH1A1GAAMEN1 | |
| SCHEMBL7977738 | 0.79 | MAPK14 (0.56) | KDM4EHPGDALDH1A1GAAMEN1 | |
| SCHEMBL7992039 | 0.79 | MAPK14 (0.56) | KDM4EHPGDALDH1A1GAAMEN1 | |
| SCHEMBL7977380 | 0.77 | MEN1 (0.56) | KDM4EHPGDALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |