Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14705875 | 0.88 | SMN1; SMN2 (0.49) | ALDH1A1KMT2AKDM4EHSD17B10NPSR1 | |
| SCHEMBL7989981 | 0.82 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2AKDM4EHSD17B10 | |
| SCHEMBL7977822 | 0.82 | KDM4E (0.47) | ALDH1A1KMT2AKDM4EHSD17B10HPGD | |
| SCHEMBL28576641 | 0.81 | ERCC1 (0.60) | ALDH1A1KMT2AKDM4EHSD17B10NPSR1 | |
| SCHEMBL7987871 | 0.77 | RAB9A (0.43) | ALDH1A1POLBKMT2AKDM4EHSD17B10 | |
| SCHEMBL7995274 | 0.76 | ALDH1A1 (0.42) | ALDH1A1POLBKMT2AKDM4EHSD17B10 | |
| SCHEMBL7995385 | 0.76 | MMP2 (0.51) | ALDH1A1POLBKMT2AKDM4EHSD17B10 | |
| SCHEMBL7977922 | 0.76 | ALDH1A1 (0.42) | ALDH1A1POLBKMT2AKDM4EHSD17B10 | |
| SCHEMBL7988684 | 0.74 | RAB9A (0.59) | ALDH1A1POLBKMT2AKDM4ERAB9A | |
| SCHEMBL6494078 | 0.73 | TARBP2 (0.56) | ALDH1A1KMT2AKDM4EHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |