Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989265 | 0.87 | SIRT2 (0.47) | CHEK2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL7989867 | 0.86 | SIRT2 (0.58) | CHEK2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL7991843 | 0.85 | AURKA (0.45) | CHEK2MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL7977819 | 0.85 | CHEK2 (0.51) | CHEK2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL7989662 | 0.84 | LMNA (0.45) | CHEK2MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL7989895 | 0.84 | CHEK2 (0.50) | CHEK2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7995495 | 0.81 | MAPK13 (0.63) | CHEK2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL15075613 | 0.81 | MAPK13 (0.63) | CHEK2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL7989394 | 0.80 | KMT2A (0.53) | CHEK2MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL7995795 | 0.79 | KMT2A (0.52) | CHEK2MAPTALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |