Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991843 | 0.88 | AURKA (0.45) | SIRT2SIRT1KMT2AALDH1A1HPGD | |
| SCHEMBL7977819 | 0.88 | CHEK2 (0.51) | SIRT2SIRT1KDM4EMEN1KMT2A | |
| SCHEMBL7977935 | 0.87 | CHEK2 (0.53) | SIRT2SIRT1KDM4EMEN1KMT2A | |
| SCHEMBL7989895 | 0.87 | CHEK2 (0.50) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL7989662 | 0.87 | LMNA (0.45) | SIRT2SIRT1KMT2AALDH1A1HPGD | |
| SCHEMBL7988152 | 0.85 | SIRT2 (0.61) | SIRT2SIRT1KDM4EMEN1KMT2A | |
| SCHEMBL7978027 | 0.82 | KDM4E (0.67) | KDM4EMEN1KMT2AALDH1A1GLA | |
| SCHEMBL7977718 | 0.81 | PRKAB2 (0.48) | ALDH1A1HPGDDGAT1SMN1; SMN2BRD4 | |
| SCHEMBL7988137 | 0.80 | PRKAB2 (0.52) | MEN1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL7992039 | 0.79 | MAPK14 (0.56) | KDM4EMEN1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |