Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648130 | 0.82 | HPGDS (0.55) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27321802 | 0.80 | RAB9A (0.63) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL3493236 | 0.79 | HPGDS (0.60) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL10172532 | 0.79 | HPGDS (0.60) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL1753182 | 0.79 | HPGDS (0.60) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL5330670 | 0.76 | HPGDS (0.56) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL9985730 | 0.75 | HPGDS (0.61) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2838238 | 0.73 | ALDH1A1 (0.54) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL11351745 | 0.72 | ALDH1A1 (0.58) | HPGDSALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL4802249 | 0.72 | KDM4E (0.60) | HPGDSALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |