Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989585 | 0.91 | TARBP2 (0.46) | KMT2AMAPTMEN1LMNATARBP2 | |
| SCHEMBL7995767 | 0.91 | KDM4E (0.49) | KMT2AMAPTMEN1LMNATARBP2 | |
| SCHEMBL7988490 | 0.89 | MAPK14 (0.53) | ALOX5KMT2AMAPTMEN1LMNA | |
| SCHEMBL7989706 | 0.88 | TARBP2 (0.49) | KMT2AMAPTMEN1LMNATARBP2 | |
| SCHEMBL7989869 | 0.87 | KDM4E (0.43) | ALOX5KMT2AMAPTMEN1LMNA | |
| SCHEMBL7977756 | 0.86 | AR (0.48) | MAPTLMNAALDH1A1ELANEHSD17B10 | |
| SCHEMBL7989339 | 0.83 | MAPK14 (0.46) | ALOX5GCGRCYP1A2CYP2C19KDM4E | |
| SCHEMBL6473195 | 0.81 | TARBP2 (0.51) | ALOX5PTGESMAPTTARBP2TP53 | |
| SCHEMBL5554927 | 0.80 | KDM4E (0.48) | KMT2AMAPTLMNATP53ALDH1A1 | |
| SCHEMBL7988187 | 0.79 | TARBP2 (0.45) | ALOX5PTGESKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |