Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | GCGR | P47871 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989585 | 0.91 | TARBP2 (0.46) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7995767 | 0.91 | KDM4E (0.49) | KDM4EKMT2AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL7977974 | 0.89 | ALOX5 (0.49) | GCGRALOX5ELANEKDM4EKMT2A | |
| SCHEMBL7989869 | 0.89 | KDM4E (0.43) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7989706 | 0.88 | TARBP2 (0.49) | KDM4EKMT2AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL7977756 | 0.86 | AR (0.48) | ELANEALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL7991880 | 0.83 | MAPK14 (0.60) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL5554927 | 0.82 | KDM4E (0.48) | ELANEKDM4EKMT2AMAPK1L3MBTL1 | |
| SCHEMBL7988187 | 0.79 | TARBP2 (0.45) | ALOX5ELANEKDM4EKMT2AALDH1A1 | |
| SCHEMBL7989451 | 0.77 | ALOX5 (0.58) | MAPK14GCGRMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |