Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 2/20 | 0.49 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989585 | 0.90 | TARBP2 (0.46) | TARBP2GAAPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7995767 | 0.90 | KDM4E (0.49) | TARBP2GAAPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7988490 | 0.88 | MAPK14 (0.53) | TARBP2GAAPOLBKDM4EKMT2A | |
| SCHEMBL7977974 | 0.88 | ALOX5 (0.49) | TARBP2KDM4EKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7989059 | 0.86 | MAPT (0.51) | GAAKDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7989869 | 0.86 | KDM4E (0.43) | KDM4EKMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL7977756 | 0.85 | AR (0.48) | GAAALDH1A1MAPTLMNARAB9A | |
| SCHEMBL7988187 | 0.82 | TARBP2 (0.45) | TARBP2GAAPOLBKDM4EKMT2A | |
| SCHEMBL5554927 | 0.79 | KDM4E (0.48) | POLBKDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7977737 | 0.78 | PRMT5 (0.57) | TARBP2PDCD4GAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |