Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991800 | 0.91 | KDM4E (0.51) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7991880 | 0.88 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7991805 | 0.88 | KDM4E (0.48) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7995032 | 0.86 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7989059 | 0.84 | MAPT (0.51) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7977712 | 0.84 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7989916 | 0.83 | IDO1 (0.50) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7977974 | 0.83 | ALOX5 (0.49) | GCGRKDM4ECYP1A2MAPK1CYP2C19 | |
| SCHEMBL7989665 | 0.80 | GPR84 (0.43) | MAPK14MAPK13MAPK12MAPK11GCGR | |
| SCHEMBL7994926 | 0.78 | RAB9A (0.45) | KDM4EPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |