Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295033 | 0.81 | MAOA (0.43) | MAOAMAOB | |
| SCHEMBL8665717 | 0.79 | AKR1B1 (0.38) | MAOAMAOB | |
| SCHEMBL9696419 | 0.78 | ABCG2 (0.39) | MAOAMAOB | |
| SCHEMBL294572 | 0.78 | MAOA (0.41) | MAOAMAOB | |
| SCHEMBL1648706 | 0.78 | KEAP1 (0.43) | MAOAMAOB | |
| SCHEMBL21615077 | 0.77 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL511051 | 0.75 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL4530544 | 0.74 | MAOA (0.37) | MAOAMAOB | |
| SCHEMBL293444 | 0.74 | MAOA (0.37) | MAOAMAOB | |
| SCHEMBL1707855 | 0.74 | MAOA (0.48) | MAOAMAOBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001072735-A2 | BENZOPYRANES USEFUL AS TNF ALPHA INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-04 | — | — | WO | disclosed |