Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714851 | 1.00 | MAOA (0.48) | MAOAMAOBESR2OXTRABCG2 | |
| SCHEMBL295062 | 0.76 | MAOA (0.50) | MAOAMAOBESR2OXTRABCG2 | |
| SCHEMBL18280613 | 0.74 | MAOA (0.48) | MAOAMAOBESR2OXTRABCG2 | |
| SCHEMBL295061 | 0.74 | MAOA (0.48) | MAOAMAOBESR2OXTRABCG2 | |
| SCHEMBL2013569 | 0.74 | MAOA (0.48) | MAOAMAOBESR2OXTRABCG2 | |
| SCHEMBL4551344 | 0.74 | MAOA (0.48) | MAOAMAOBESR2OXTRABCG2 | |
| SCHEMBL276642 | 0.74 | MAOA (0.48) | MAOAMAOBOXTRABCG2ITGB2 | |
| SCHEMBL224499 | 0.74 | MAOA (0.48) | MAOAMAOBESR2OXTRABCG2 | |
| SCHEMBL7977979 | 0.74 | MAOA (0.43) | MAOAMAOBESR2 | |
| SCHEMBL16397646 | 0.72 | MAOA (0.42) | MAOAMAOBOXTRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423405-A | Method for synthesizing benzopyran 3 alcohol derivative compound | 浙江工业大学 | 2020-07-17 | — | — | CN | claimed |
| JP-3575767-B2 | — | — | 2004-10-13 | — | — | JP | claimed |
| EP-0764157-A1 | BENZOPYRANS AND THEIR USE AS THERAPEUTIC AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-26 | — | — | EP | claimed |
| WO-1995034545-A1 | BENZOPYRANS AND THEIR USE AS THERAPEUTIC AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-21 | — | — | WO | claimed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | claimed |
| EP-0673373-A1 | BICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-09-27 | — | — | EP | claimed |
| EP-0413438-A1 | Benzopyran compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | claimed |
| WO-2026088071-A1 | SUBSTITUTED FUSED HETEROARYL LACTAM COMPOUNDS | PFIZER INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| CN-111423405-B | Method for synthesizing benzopyran 3 alcohol derivative compound | 浙江工业大学 | 2021-11-26 | — | — | CN | disclosed |
| CN-111423405-A | Method for synthesizing benzopyran 3 alcohol derivative compound | 浙江工业大学 | 2020-07-17 | — | — | CN | disclosed |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | LIBRAGEN (FR) | 2014-03-27 | — | — | US | disclosed |
| EP-2027279-B1 | Phenolic compounds with cosmetic and therapeutic applications | LIBRAGEN (FR) | 2012-04-18 | — | — | EP | disclosed |
| US-20110183930-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | LIBRAGEN (FR) | 2011-07-28 | — | — | US | disclosed |
| EP-0547523-A1 | Ethanolates of 6-sulfonylsubstituted 3-hydroxychromanes and their use as inhalation means for illnesses | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | disclosed |
| WO-1993005045-A1 | SPIROCYCLIC BENZOPYRAN IMIDAZOLINES | THE UPJOHN COMPANY (US) | 1993-03-18 | — | — | WO | disclosed |
| EP-0516658-A1 | BENZOPYRANS HAVING PHARMACOLOGICAL ACTIVITY | BEECHAM GROUP PLC (GB) | 1992-12-09 | — | — | EP | disclosed |
| WO-1991011446-A1 | BENZOPYRANS HAVING PHARMACOLOGICAL ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| EP-0412760-A2 | Benzopyran derivatives | Beecham Group p.l.c. (GB) | 1991-02-13 | — | — | EP | disclosed |
| EP-0373204-A1 | NOVEL COMPOUNDS AND TREATMENT | BEECHAM GROUP PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
| WO-1989010925-A1 | NOVEL COMPOUNDS AND TREATMENT | BEECHAM GROUP PLC (GB) | 1989-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183930-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | UGGT1, TYR, G6PD | MAOA 688/4885MAOB 981/4885ESR2 2662/4885 |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | UGGT1, TYR, G6PD | MAOA 688/4885MAOB 981/4885ESR2 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.