Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998415 | 0.97 | KDM4E (0.39) | KDM4EALDH1A1GAACSNK1DLMNA | |
| SCHEMBL7996112 | 0.85 | RAB9A (0.51) | KDM4EALDH1A1GAACSNK1DLMNA | |
| SCHEMBL7997959 | 0.83 | KDR (0.43) | KDM4EALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7997945 | 0.83 | SMN1; SMN2 (0.36) | KDM4EALDH1A1GAACSNK1DLMNA | |
| SCHEMBL6100730 | 0.82 | MAPT (0.40) | KDM4EALDH1A1GAACSNK1DSMN1; SMN2 | |
| SCHEMBL7232438 | 0.81 | GLS (0.43) | KDM4EALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL7998311 | 0.80 | GLS (0.44) | KDM4EALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL7230936 | 0.80 | GAA (0.47) | ALDH1A1GAACSNK1D | |
| SCHEMBL7984009 | 0.80 | CACNA1H (0.38) | CSNK1DMAPK10RAB9A | |
| SCHEMBL7984012 | 0.80 | TRPV1 (0.37) | KDM4EALDH1A1GAACSNK1DMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055140-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |