SCHEMBL7978089

SCHEMBL7978089

C[CH]Oc1c(F)ccc(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547886 0.78 NFE2L2 (0.36) CES2CES1
SCHEMBL1343625 0.78 ALDH1A1 (0.33)
SCHEMBL15759433 0.76 CES2 (0.33) CES2CES1
SCHEMBL1997466 0.76 CES2 (0.38) CES2CES1
SCHEMBL1994314 0.72 MEP1B (0.41) CES2CES1
SCHEMBL1547745 0.68 SLC6A2 (0.43) CES2CES1
SCHEMBL15759393 0.68 CES2 (0.35) CES2CES1
SCHEMBL6513585 0.67 CES2 (0.37) CES2CES1
SCHEMBL22114350 0.67 NQO1 (0.40) CES2CES1
SCHEMBL8570914 0.67 SLC6A2 (0.41) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001036367-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2001-05-25 WO disclosed