Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | PLG | P00747 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029668 | 0.84 | PIK3CD (0.46) | F2USP30BRD4PIK3CDHDAC8 | |
| SCHEMBL7426210 | 0.83 | F2 (0.46) | F2F10PLGKMT2AKDM4E | |
| SCHEMBL7981348 | 0.80 | BRPF1 (0.56) | F2BRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7982026 | 0.80 | F2 (0.65) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7981313 | 0.80 | ALDH1A1 (0.44) | F2F10PLGMEN1KMT2A | |
| SCHEMBL7968222 | 0.78 | ALDH1A1 (0.38) | F2F10PLGBRD4KDM4E | |
| SCHEMBL7426354 | 0.78 | F2 (0.55) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7426925 | 0.78 | F2 (0.72) | F2F10PLGHDAC6ALDH1A1 | |
| SCHEMBL7978111 | 0.76 | F2 (0.44) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7981516 | 0.75 | BRPF1 (0.42) | F2F10PLGBRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |