Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967399 | 0.89 | RAB9A (0.40) | KDM4EL3MBTL1RAB9AKMT2ANPC1 | |
| SCHEMBL7979468 | 0.77 | MAPT (0.60) | KDM4ERAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8200233 | 0.76 | CYP17A1 (0.45) | CYP17A1RAB9ANPC1IKBKETBK1 | |
| SCHEMBL7976377 | 0.74 | HTT (0.56) | KDM4EL3MBTL1RAB9AKMT2ANPC1 | |
| SCHEMBL8201250 | 0.74 | CYP17A1 (0.43) | CYP17A1KMT2ANPC1MEN1NAMPT | |
| SCHEMBL8195677 | 0.73 | KMT2A (0.39) | KDM4EL3MBTL1RAB9AKMT2ANPC1 | |
| SCHEMBL8220313 | 0.73 | POLB (0.45) | RAB9AKMT2ASMN1; SMN2MEN1NAMPT | |
| SCHEMBL7979087 | 0.72 | HDAC3 (0.38) | KDM4EL3MBTL1RAB9AKMT2ANPC1 | |
| SCHEMBL7977138 | 0.72 | HDAC3 (0.38) | KDM4EL3MBTL1RAB9AKMT2ANPC1 | |
| SCHEMBL7983311 | 0.72 | HDAC3 (0.38) | KDM4EL3MBTL1RAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | claimed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | claimed |
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |