Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978653 | 1.00 | CYP11B2 (0.43) | CYP11B2CYP11B1CYP19A1VCPAR | |
| SCHEMBL7966319 | 0.88 | CYP11B1 (0.40) | CYP11B2CYP11B1CYP19A1ARCYP17A1 | |
| SCHEMBL7966320 | 0.88 | CYP11B1 (0.40) | CYP11B2CYP11B1CYP19A1ARCYP17A1 | |
| SCHEMBL7976689 | 0.87 | CYP19A1 (0.41) | CYP11B2CYP11B1CYP19A1PTAFR | |
| SCHEMBL8019943 | 0.87 | CYP19A1 (0.41) | CYP11B2CYP11B1CYP19A1PTAFR | |
| SCHEMBL7976694 | 0.87 | CYP19A1 (0.41) | CYP11B2CYP11B1CYP19A1PTAFR | |
| SCHEMBL7980127 | 0.86 | MMP12 (0.47) | CYP11B2CYP11B1CYP19A1VCPCYP17A1 | |
| SCHEMBL7980395 | 0.86 | MMP12 (0.47) | CYP11B2CYP11B1CYP19A1VCPCYP17A1 | |
| SCHEMBL7966621 | 0.86 | MMP12 (0.47) | CYP11B2CYP11B1CYP19A1VCPCYP17A1 | |
| SCHEMBL7966623 | 0.86 | MMP12 (0.47) | CYP11B2CYP11B1CYP19A1VCPCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |