Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | PRKCI | P41743 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948083 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10GLAHPGDMAPT | |
| SCHEMBL634894 | 0.74 | PARP1 (0.53) | ALDH1A1PARP1GLAHPGDMAPT | |
| Phthalazinone SCHEMBL51553 | 0.74 | PARP1 (1.00) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL9686737 | 0.72 | GAA (0.63) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| Phthalazinone SCHEMBL11516881 | 0.72 | PARP1 (0.96) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| Phthalazinone SCHEMBL4663241 | 0.72 | PARP1 (0.96) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| Phthalazinone SCHEMBL2473799 | 0.72 | PARP1 (0.96) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| Phthalazinone SCHEMBL9617397 | 0.72 | PARP1 (0.96) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| Phthalazinone SCHEMBL2962226 | 0.72 | PARP1 (0.96) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| Phthalazinone SCHEMBL11690359 | 0.72 | PARP1 (0.96) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214826-B1 | NERVOUS SYSTEM DISORDERS | ZENECA LIMITED (GB) | 2001-04-10 | — | — | US | disclosed |
| EP-0790996-A1 | PYRIDAZINOQUINOLINE COMPOUNDS | ZENECA LIMITED (GB) | 1997-08-27 | — | — | EP | disclosed |