Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PTGIR | P43119 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982394 | 0.86 | PTGIR (0.46) | HTTPTGIRNPC1CYP1A2CYP2C9 | |
| SCHEMBL27511353 | 0.83 | NPC1 (0.42) | HTTPTGIRNPC1LMNACYP1A2 | |
| SCHEMBL7978952 | 0.83 | ALDH1A1 (0.45) | HTTPTGIRNPC1LMNACYP1A2 | |
| SCHEMBL7978997 | 0.76 | HTT (0.41) | HTTNPC1LMNARAB9AKMT2A | |
| SCHEMBL7969122 | 0.71 | HTT (0.42) | HTTNPC1RAB9AKMT2ANPSR1 | |
| SCHEMBL7978994 | 0.71 | NPSR1 (0.41) | HTTPTGIRNPC1RAB9AKMT2A | |
| SCHEMBL7980229 | 0.71 | NPC1 (0.66) | HTTPTGIRNPC1LMNACYP1A2 | |
| SCHEMBL7981944 | 0.71 | PTGIR (0.46) | HTTPTGIRNPC1RAB9AKMT2A | |
| SCHEMBL7978941 | 0.69 | TP53 (0.51) | HTTPTGIRNPC1RAB9AKMT2A | |
| SCHEMBL28682606 | 0.69 | PTGIR (0.44) | HTTPTGIRNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |