Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.76 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394926 | 0.87 | MMP3 (1.00) | MMP3KAT6ACNR1NAMPTTRPV1 | |
| SCHEMBL7990098 | 0.74 | MMP3 (0.77) | MMP3KAT6ATRPV1 | |
| SCHEMBL7979094 | 0.73 | MMP3 (0.50) | MMP3 | |
| SCHEMBL26920561 | 0.72 | GAA (0.56) | MMP3POLBL3MBTL1 | |
| SCHEMBL7993192 | 0.71 | KIF11 (0.48) | MMP3ADAMTS4L3MBTL1 | |
| SCHEMBL7993862 | 0.71 | MMP3 (0.71) | MMP3KAT6A | |
| SCHEMBL27438205 | 0.71 | KEAP1 (0.58) | L3MBTL1 | |
| SCHEMBL5597888 | 0.68 | GAA (0.71) | NAMPTPOLB | |
| SCHEMBL5598318 | 0.68 | POLB (0.60) | MMP3NAMPTTRPV1POLBL3MBTL1 | |
| SCHEMBL5598267 | 0.68 | NAMPT (0.53) | MMP3NAMPTADAMTS4MMP13L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |