Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RHOC | P08134 | 3/20 | 0.34 |
| ▸ | RHOA | P61586 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | BLK | P51451 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982119 | 0.97 | HTT (0.34) | HTTRHOCRHOASCN9ASIGMAR1 | |
| SCHEMBL8408424 | 0.94 | HTT (0.38) | HTTRHOCRHOASCN9ASIGMAR1 | |
| SCHEMBL8659999 | 0.91 | HTT (0.37) | HTTRHOCRHOASCN9ASIGMAR1 | |
| SCHEMBL7979272 | 0.89 | HTT (0.38) | HTTRHOCRHOASIGMAR1 | |
| SCHEMBL7979390 | 0.89 | SCN8A (0.38) | HTTRHOCRHOASCN9ASCN8A | |
| SCHEMBL7965701 | 0.86 | HTT (0.37) | HTTRHOCRHOASIGMAR1 | |
| SCHEMBL7965856 | 0.86 | RHOC (0.48) | HTTRHOCRHOAJAK1BLK | |
| SCHEMBL7976122 | 0.86 | HTT (0.36) | HTTRHOCRHOASCN9ASCN8A | |
| SCHEMBL7979247 | 0.85 | HTT (0.38) | HTTRHOCRHOASCN9ASIGMAR1 | |
| SCHEMBL7979279 | 0.85 | MAPT (0.36) | HTTRHOCRHOASCN9ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |