Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 1.00 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397190 | 0.84 | MMP3 (1.00) | MMP3POLBMMP9MMP1MMP2 | |
| SCHEMBL7990504 | 0.81 | MMP3 (1.00) | MMP3MMP1 | |
| SCHEMBL7996909 | 0.79 | MMP3 (1.00) | MMP3MMP1 | |
| SCHEMBL7394926 | 0.78 | MMP3 (1.00) | MMP3MMP9MMP1MMP2MMP14 | |
| SCHEMBL7389205 | 0.74 | MMP3 (1.00) | MMP3MEP1BMMP9MMP1MMP2 | |
| SCHEMBL7990098 | 0.73 | MMP3 (0.77) | MMP3 | |
| SCHEMBL13234517 | 0.73 | KCNA5 (0.72) | ALDH1A1KCNA5KCNH2SMN1; SMN2 | |
| SCHEMBL7386826 | 0.72 | MMP3 (1.00) | MMP3MEP1BALDH1A1MMP9MMP1 | |
| SCHEMBL7398557 | 0.71 | MMP3 (1.00) | MMP3 | |
| SCHEMBL7389210 | 0.70 | MMP3 (0.90) | MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | claimed |
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |