Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 15/20 | 1.00 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | MMP16 | P51512 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398298 | 0.88 | MMP3 (1.00) | MMP3MMP1MMP9MMP2MMP13 | |
| SCHEMBL7397190 | 0.82 | MMP3 (1.00) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL7997116 | 0.82 | MMP3 (0.69) | MMP3MMP9MMP2MMP12MMP14 | |
| SCHEMBL7392568 | 0.80 | MMP3 (1.00) | MMP3 | |
| SCHEMBL7990560 | 0.76 | MMP3 (0.79) | MMP3MMP1MMP9MMP2MMP13 | |
| SCHEMBL7979268 | 0.74 | MMP3 (1.00) | MMP3MMP1MMP9MMP2MMP8 | |
| SCHEMBL7993608 | 0.74 | MMP3 (0.94) | MMP3MMP1MMP9MMP2MMP13 | |
| SCHEMBL7997139 | 0.73 | MMP3 (0.72) | MMP3 | |
| SCHEMBL11841026 | 0.73 | MMP3 (0.55) | MMP3 | |
| SCHEMBL7993523 | 0.71 | MMP3 (0.70) | MMP3MMP9MMP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | claimed |
| WO-2000037433-A1 | INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-06-29 | — | — | WO | claimed |
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |