Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 14/20 | 1.00 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | MMP16 | P51512 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979268 | 0.84 | MMP3 (1.00) | MMP3MMP9MMP1MMP2MMP8 | |
| SCHEMBL7996909 | 0.83 | MMP3 (1.00) | MMP3MMP1MTNR1AHDAC1HDAC8 | |
| SCHEMBL7389205 | 0.82 | MMP3 (1.00) | MMP3MMP9MMP1MMP2MMP8 | |
| SCHEMBL7990504 | 0.81 | MMP3 (1.00) | MMP3MMP1HDAC1HDAC8KMT2A | |
| SCHEMBL7990098 | 0.75 | MMP3 (0.77) | MMP3 | |
| SCHEMBL7389210 | 0.74 | MMP3 (0.90) | MMP3HDAC1HDAC8 | |
| SCHEMBL7996699 | 0.73 | MMP3 (0.76) | MMP3KMT2A | |
| SCHEMBL7398557 | 0.71 | MMP3 (1.00) | MMP3HDAC1HDAC8 | |
| SCHEMBL7993209 | 0.71 | MMP3 (0.79) | MMP3MTNR1AHDAC1HDAC8KMT2A | |
| SCHEMBL7394926 | 0.71 | MMP3 (1.00) | MMP3MMP9MMP1MMP2MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | claimed |
| WO-2000037433-A1 | INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-06-29 | — | — | WO | claimed |
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |