Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979619 | 0.83 | TDP1 (0.48) | TDP1PGRMDM2CA12CA9 | |
| SCHEMBL7979708 | 0.77 | TDP1 (0.49) | TDP1PGRBRD4HTR2C | |
| SCHEMBL11735010 | 0.71 | CASP1 (0.41) | TDP1MAPT | |
| SCHEMBL11729888 | 0.70 | MAOB (0.40) | TDP1MAPT | |
| SCHEMBL7650360 | 0.70 | NR1H2 (0.43) | TDP1PGR | |
| Hydrochloric Acid SCHEMBL11732130 | 0.69 | TDP1 (0.40) | TDP1MAPT | |
| SCHEMBL9773598 | 0.68 | ELANE (0.43) | PGRELANE | |
| SCHEMBL5784952 | 0.68 | ADRA1D (0.64) | ADRA1DADRA1AADRA1BMDM2CA12 | |
| SCHEMBL8122536 | 0.66 | ALDH1A1 (0.53) | MAPT | |
| SCHEMBL13233765 | 0.66 | ELANE (0.58) | TDP1PGRELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |