Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 5/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | BRD1 | O95696 | 3/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.41 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7977859 | 0.83 | F2 (0.49) | TDP1 | |
| SCHEMBL7979527 | 0.77 | TDP1 (0.51) | TDP1HTR2CBRD4PGR | |
| SCHEMBL7979619 | 0.74 | TDP1 (0.48) | TDP1CYP19A1PGR | |
| SCHEMBL7479090 | 0.70 | BRPF1 (0.52) | BRPF1ARSMARCA2IMPDH2BRD4 | |
| SCHEMBL7572258 | 0.69 | CYP19A1 (0.75) | ARCYP19A1PGRMEN1KMT2A | |
| SCHEMBL7428683 | 0.69 | BRPF1 (0.52) | BRPF1ARSMARCA2IMPDH2BRD4 | |
| SCHEMBL7981601 | 0.67 | BRPF1 (0.51) | BRPF1ARSMARCA2IMPDH2BRD4 | |
| SCHEMBL8029898 | 0.66 | BRPF1 (0.61) | BRPF1ARSMARCA2IMPDH2BRD4 | |
| SCHEMBL5784952 | 0.66 | ADRA1D (0.64) | BRD4KMT2A | |
| SCHEMBL8028568 | 0.65 | F2 (0.61) | BRPF1ARSMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |