Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982358 | 0.81 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14921847 | 0.80 | OPRM1 (0.55) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14399666 | 0.75 | HTR2A (0.53) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL30171037 | 0.75 | ATM (0.54) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4212837 | 0.75 | ATM (0.54) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL350321 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL6394938 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL27474102 | 0.73 | LMNA (0.58) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL26978217 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL10617441 | 0.72 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |