Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301469 | 0.88 | HPGDS (0.71) | HPGDSLTA4HHDAC4NPC1RAB9A | |
| SCHEMBL28753616 | 0.86 | HPGDS (0.69) | HPGDSLTA4HHDAC4NPC1RAB9A | |
| SCHEMBL533033 | 0.84 | LTA4H (0.50) | HPGDSLTA4HHDAC4BRD4CHRNA7 | |
| SCHEMBL5571760 | 0.84 | LTA4H (0.70) | HPGDSLTA4HHDAC4NPC1RAB9A | |
| SCHEMBL1152211 | 0.81 | HPGDS (0.50) | HPGDSLTA4HHDAC4BRD4CHRNA7 | |
| SCHEMBL5323135 | 0.81 | LTA4H (0.51) | HPGDSLTA4HHDAC4NOTUMBRD4 | |
| Toluene SCHEMBL28904988 | 0.79 | HPGDS (0.61) | HPGDSLTA4HHDAC4NPC1RAB9A | |
| Piperazine SCHEMBL3360835 | 0.78 | HPGDS (0.59) | HPGDSLTA4HHDAC4NPC1RAB9A | |
| Perchlorate SCHEMBL9472619 | 0.78 | HPGDS (0.59) | HPGDSLTA4HHDAC4NPC1RAB9A | |
| Thiophene SCHEMBL19467814 | 0.78 | HPGDS (0.59) | HPGDSLTA4HHDAC4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297267-B1 | PROSTAGLANDIN I2 AGONIST. | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-02 | — | — | US | disclosed |