SCHEMBL533033

SCHEMBL533033

[c]1ccc(-c2ncco2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.50
HPGDS O60760 1/20 0.47
HDAC4 P56524 1/20 0.41
CHRNA7 P36544 1/20 0.40
CHRNA10 Q9GZZ6 1/20 0.40
CHRNA9 Q9UGM1 1/20 0.40
KCNJ1 P48048 1/20 0.35
KCNH2 Q12809 1/20 0.35
BRD4 O60885 2/20 0.33
GLRA3 O75311 1/20 0.33
GLRB P48167 1/20 0.33
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
ADRB3 P13945 1/20 0.32
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31
PIN1 Q13526 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5323135 0.96 LTA4H (0.51) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL7979723 0.84 HPGDS (0.59) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL722557 0.84 LTA4H (0.64) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL28362996 0.81 LTA4H (0.62) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL28320605 0.81 LTA4H (0.62) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL28257875 0.81 LTA4H (0.62) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL3222694 0.77 LTA4H (0.53) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL301469 0.77 HPGDS (0.71) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL747313 0.76 HPGDS (0.46) LTA4HHPGDSHDAC4CHRNA7CHRNA10
SCHEMBL1152211 0.76 HPGDS (0.50) LTA4HHPGDSHDAC4CHRNA7CHRNA10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 721 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132531-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2024-04-25 US claimed
CN-117043156-A Novel galectin inhibitors of galectins 格莱克特生物技术公司 2023-11-10 CN claimed
EP-4267570-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2023-11-01 EP claimed
EP-4267568-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2023-11-01 EP claimed
CN-116710447-A Novel galectin inhibitors of galectins 格莱克特生物技术公司 2023-09-05 CN claimed
WO-2023118267-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2023-06-29 WO claimed
WO-2023060573-A1 NOVEL THIADIAZOLYL DERIVATIVES OF DNA POLYMERASE THETA INHIBITORS BEIJING DANATLAS PHARMACEUTICAL CO., LTD. (CN) 2023-04-20 WO claimed
WO-2022144274-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2022-07-07 WO claimed
WO-2022136365-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2022-06-30 WO claimed
EP-3994135-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2022-05-11 EP claimed
EP-1140895-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP claimed
WO-2001060808-A1 THIAZEPINYL HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-08-23 WO claimed
WO-2000040576-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-13 WO claimed
US-5977075-A N-aroylamino acid amides as endothelin inhibitors NOVARTIS AG (CH) 1999-11-02 US claimed
CN-1195050-A Method for reducing the color and polymerization degree decline of cellulose mucus JULONG FIBRE CO LTD (CN) 1998-10-07 CN claimed
US-5756493-A ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA MICROCIDE PHARMACEUTICALS, INC. (US) 1998-05-26 US claimed
EP-0821670-A1 N-AROYLAMINO ACID AMIDES AS ENDOTHELIN INHIBITORS Novartis AG (CH) 1998-02-04 EP claimed
WO-1996033170-A1 N-AROYLAMINO ACID AMIDES AS ENDOTHELIN INHIBITORS NOVARITS AG (CH) 1996-10-24 WO claimed
EP-0728145-A1 ENDOTHELIN RECEPTOR ANTAGONISTS Ciba-Geigy Japan Limited (JP) 1996-08-28 EP claimed
WO-1995012611-A1 ENDOTHELIN RECEPTOR ANTAGONISTS JAPAT LTD. (CH) 1995-05-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132531-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS LGALS1, LGALS3, LGALS3BP LTA4H 1175/4885HPGDS 845/4885HDAC4 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.