Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997324 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL7991911 | 0.97 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL7994325 | 0.97 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL18461191 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL13498610 | 0.77 | CA1 (0.55) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL5498052 | 0.77 | CA1 (0.55) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL2481338 | 0.74 | GSK3B (0.47) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL27587477 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPT | |
| SCHEMBL10380361 | 0.72 | L3MBTL1 (0.63) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL17233757 | 0.72 | CA1 (0.51) | SMN1; SMN2ALDH1A1MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297267-B1 | PROSTAGLANDIN I2 AGONIST. | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-02 | — | — | US | disclosed |