SCHEMBL27587477

SCHEMBL27587477

O=C(O)c1ccc(C(=O)OCC2CCCCC2OC(=O)c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
SERPINE1 P05121 2/20 0.41
SLC18A3 Q16572 1/20 0.40
CHRNB2 P17787 3/20 0.40
CHRNA7 P36544 3/20 0.40
CHRNA4 P43681 3/20 0.40
CHRNA5 P30532 2/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
MAPT P10636 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27467741 0.83 SERPINE1 (0.56) ALDH1A1KMT2AMEN1SERPINE1SLC18A3
SCHEMBL2423060 0.82 CHRNB2 (0.42) ALDH1A1KMT2AMEN1CHRNB2CHRNA7
SCHEMBL11452756 0.81 SERPINE1 (0.54) ALDH1A1KMT2AMEN1SERPINE1SLC18A3
SCHEMBL2296496 0.77 DRD2 (0.49) KMT2AMEN1CHRNB2CHRNA7CHRNA4
SCHEMBL9245106 0.76 ALDH1A1 (0.45) ALDH1A1KMT2AMEN1SERPINE1SLC18A3
SCHEMBL9548164 0.75 DRD2 (0.52) ALDH1A1CHRNB2CHRNA7CHRNA4CHRNA5
SCHEMBL7979731 0.74 SMN1; SMN2 (0.51) ALDH1A1MAPT
SCHEMBL7997324 0.74 SMN1; SMN2 (0.51) ALDH1A1MAPT
SCHEMBL4654745 0.74 PARP15 (0.45) ALDH1A1KMT2AMEN1
SCHEMBL31319176 0.73 STS (0.59) ALDH1A1KMT2AMEN1CHRNA7MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1628346-A Color data storage medium GEN ELECTRIC COMPANY A CORP OF (US) 2005-06-15 CN claimed
CN-102076766-B Polymer compositions, method of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP 2014-04-30 CN disclosed
CN-1906489-B Optical storage medium with polymer film containing analyte and use thereof GENERAL ELECTRIC CO. (US) 2011-12-14 CN disclosed
CN-102076766-A Polymer compositions, method of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP 2011-05-25 CN disclosed
CN-100478826-C Authenticable optical disc, optical disc authentication system and method GEN ELECTRIC (NL) 2009-04-15 CN disclosed
CN-100468541-C Method for making highly colored DVDs GEN ELECTRIC (NL) 2009-03-11 CN disclosed
CN-101258625-A Devices and methods capable of authenticating batteries GEN ELECTRIC (US) 2008-09-03 CN disclosed
CN-100391620-C Spin coated media GEN ELECTRIC (US) 2008-06-04 CN disclosed
CN-1906489-A Optical storage medium with polymer film containing analyte and use thereof GEN ELECTRIC (US) 2007-01-31 CN disclosed
CN-1898301-A Dry powder colorant mixing and dispensing method JETTA COMPANY LTD (HK) 2007-01-17 CN disclosed
CN-1886710-A Authenticable optical disc, system for authenticating an optical disc and method thereof GEN ELECTRIC (US) 2006-12-27 CN disclosed
CN-1871646-A Method for manufacturing highly colored DVD GEN ELECTRIC (US) 2006-11-29 CN disclosed
CN-1628346-A Color data storage medium GEN ELECTRIC COMPANY A CORP OF (US) 2005-06-15 CN disclosed
CN-1525888-A Spin coated media 通用电气公司 2004-09-01 CN disclosed