Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974397 | 0.84 | SMN1; SMN2 (0.50) | LMNAMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7977585 | 0.81 | POLB (0.48) | LMNAMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7975313 | 0.80 | LMNA (0.44) | LMNAMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7963977 | 0.79 | LMNA (0.49) | KDM4ELMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL7974484 | 0.79 | MAPT (0.45) | LMNAMAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7975290 | 0.79 | LMNA (0.50) | LMNAMAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7974305 | 0.78 | MAPT (0.53) | LMNAMAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7977628 | 0.78 | LMNA (0.47) | LMNAMAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7975380 | 0.78 | LMNA (0.47) | LMNAMAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7974463 | 0.77 | LMNA (0.46) | LMNAMAPTSMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |