Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29235466 | 0.82 | TP53 (0.46) | GABRA5GABRA1LCKCHUKPARP1 | |
| SCHEMBL2468642 | 0.82 | DAO (0.46) | DAOGABRA5GABRPGABRDGABRA1 | |
| SCHEMBL7982949 | 0.82 | GABRA5 (0.36) | DAOGABRA5GABRA1PARP1 | |
| SCHEMBL29235602 | 0.78 | PARP1 (0.45) | KDM4EPARP1 | |
| SCHEMBL7983014 | 0.78 | GABRA5 (0.46) | KDM4EGABRA5GABRA1ACHELCK | |
| SCHEMBL30095396 | 0.78 | PARP1 (0.59) | DAOKDM4EGABRA5GABRA1PARP1 | |
| SCHEMBL4763948 | 0.78 | PARP1 (0.59) | DAOKDM4EGABRA5GABRA1PARP1 | |
| SCHEMBL11997319 | 0.77 | IDO1 (0.40) | GABRA5GABRA1PARP1 | |
| SCHEMBL7969955 | 0.77 | GRIA1 (0.51) | GABRA5GABRA1GABRG2GABRB3GABRA2 | |
| SCHEMBL31026839 | 0.77 | TP53 (0.35) | DAOGABRA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |