Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981201 | 0.83 | LMNA (0.57) | CYP1A1CYP1A2CYP1B1MAPTTUBB1 | |
| SCHEMBL9372014 | 0.78 | NFE2L2 (0.44) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL21415991 | 0.74 | CA1 (0.55) | CYP1A1CYP1A2CYP1B1MAPTKMT2A | |
| SCHEMBL17164790 | 0.74 | CA1 (0.55) | CYP1A1CYP1A2CYP1B1MAPTKMT2A | |
| SCHEMBL7980865 | 0.74 | LCK (0.46) | MAPTKMT2AMEN1TUBB1TUBB4A | |
| SCHEMBL8724172 | 0.73 | KDM4E (0.60) | CYP1A2MAPTALDH1A1TDP1HPGD | |
| SCHEMBL8724175 | 0.73 | KDM4E (0.60) | CYP1A2MAPTALDH1A1TDP1HPGD | |
| SCHEMBL9372017 | 0.72 | TNF (0.46) | MAPTKMT2AMEN1TDP1LMNA | |
| SCHEMBL4541307 | 0.71 | CYP19A1 (0.62) | MAPTKMT2AMEN1ALDH1A1TUBB1 | |
| SCHEMBL4532731 | 0.71 | CYP3A4 (0.53) | MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |