Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | PRKACG | P22612 | 1/20 | 0.53 |
| ▸ | PRKACB | P22694 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970608 | 0.82 | SRC (0.50) | SRCALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7980269 | 0.80 | CYP19A1 (0.43) | ALDH1A1MAPK1MAPTSMN1; SMN2CYP19A1 | |
| SCHEMBL7970968 | 0.77 | TSHR (0.47) | SRCALDH1A1KMT2AMAPK1MAPT | |
| SCHEMBL7983968 | 0.73 | SRC (0.56) | SRCPRKACAPRKACGPRKACBALDH1A1 | |
| SCHEMBL7984408 | 0.73 | SRC (0.51) | SRCPRKACAPRKACGPRKACBALDH1A1 | |
| SCHEMBL7970472 | 0.73 | SRC (0.55) | SRCPRKACAPRKACGPRKACBALDH1A1 | |
| SCHEMBL7981866 | 0.70 | SRC (0.55) | SRCALDH1A1KMT2AMAPK1MAPT | |
| SCHEMBL7983971 | 0.70 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL7980253 | 0.70 | SRC (0.55) | SRCALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL7987262 | 0.70 | SRC (0.50) | SRCPRKACAPRKACGPRKACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |