Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970608 | 0.78 | SRC (0.50) | ALDH1A1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL7983968 | 0.72 | SRC (0.56) | ALDH1A1GAAMAPTTP53KDM4E | |
| SCHEMBL7980269 | 0.71 | CYP19A1 (0.43) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7980441 | 0.70 | SRC (0.53) | ALDH1A1LMNACYP19A1NQO2GAA | |
| SCHEMBL7983976 | 0.70 | NOX4 (0.49) | ALDH1A1LMNAGAAMAPTHTR6 | |
| SCHEMBL7987262 | 0.68 | SRC (0.50) | ALDH1A1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL7970968 | 0.68 | TSHR (0.47) | ALDH1A1MAPTTP53KDM4EHTT | |
| SCHEMBL7980685 | 0.67 | SRC (0.59) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28603201 | 0.67 | NPY2R (0.42) | ALDH1A1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL7988065 | 0.65 | SRC (0.54) | ALDH1A1LMNAGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |