Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | HTR2B | P41595 | 5/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892901 | 0.84 | PLAU (0.43) | SIGMAR1PLAU | |
| SCHEMBL5256851 | 0.76 | PDPK1 (0.39) | SIGMAR1PDPK1 | |
| SCHEMBL6026793 | 0.75 | SIGMAR1 (0.54) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL121704 | 0.74 | PDPK1 (0.43) | SIGMAR1PDPK1 | |
| SCHEMBL1970744 | 0.73 | IDO1 (0.41) | SIGMAR1PDPK1 | |
| SCHEMBL8332242 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL4904876 | 0.71 | SIGMAR1 (0.43) | PRCPSIGMAR1TSHR | |
| SCHEMBL3653495 | 0.69 | PLAU (0.41) | PDPK1HTR2CHTR2BPLAUTSHR | |
| SCHEMBL2183528 | 0.69 | PDPK1 (0.37) | PDPK1PLAUTSHR | |
| SCHEMBL1383876 | 0.69 | ANPEP (0.39) | PDPK1PLAUTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313117-B1 | TREATING AUTOIMMUNE DISORDERS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2001-11-06 | — | — | US | claimed |