Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10106419 | 0.77 | MAPT (0.65) | KMT2AMEN1POLBSENP1MAPT | |
| SCHEMBL7980736 | 0.77 | RAB9A (0.47) | SENP1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5179218 | 0.73 | EPHX2 (0.52) | KMT2APOLBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3092388 | 0.70 | KMT2A (0.63) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL11158358 | 0.70 | MAPT (0.58) | KMT2AMEN1POLBSENP1MAPT | |
| SCHEMBL498032 | 0.70 | EGFR (0.61) | KMT2AMEN1POLBSENP1MAPT | |
| SCHEMBL6581961 | 0.70 | LMNA (0.44) | KMT2AMEN1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL14435084 | 0.70 | KMT2A (0.59) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL30353836 | 0.70 | KMT2A (0.59) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL2773071 | 0.69 | PPARA (0.59) | KMT2AMEN1POLBSENP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |