Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985032 | 0.85 | LNPEP (0.35) | HTTSMN1; SMN2HSD17B10LNPEPKDM4E | |
| SCHEMBL8500830 | 0.80 | LNPEP (0.47) | HTTSMN1; SMN2HSD17B10LNPEPKDM4E | |
| SCHEMBL8500706 | 0.76 | LNPEP (0.44) | HTTSMN1; SMN2HSD17B10LNPEPKDM4E | |
| SCHEMBL21169530 | 0.75 | CYP1A2 (0.38) | LNPEPKDM4ELOXLOXL2NOS3 | |
| SCHEMBL17733685 | 0.73 | TDP1 (0.42) | SMN1; SMN2KDM4EALDH1A1L3MBTL1TDP1 | |
| SCHEMBL22589191 | 0.73 | LOX (0.49) | HTTSMN1; SMN2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL29489548 | 0.73 | LOX (0.49) | HTTSMN1; SMN2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL511705 | 0.70 | LOXL2 (0.40) | LOXLOXL2GRM5NOS3NOS1 | |
| SCHEMBL14535556 | 0.69 | NOS3 (0.55) | KDM4ELOXLOXL2NOS3NOS1 | |
| SCHEMBL28056162 | 0.69 | MAOA (0.44) | LOXLOXL2GRM5NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001004109-A1 | PROCESS FOR THE PRODUCTION OF 2-(2-PYRIDINYLMETHYLSULPHINYL)-1H-BENZIMIDAZOLES | QUIMICA SINTETICA, S.A. (ES) | 2001-01-18 | — | — | WO | disclosed |