Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924490 | 0.81 | KDM4E (0.48) | SMN1; SMN2LMNAHTTKDM4EMMP1 | |
| SCHEMBL10153980 | 0.79 | ADAMTS4 (0.62) | SMN1; SMN2LMNAHTTKDM4EMMP1 | |
| SCHEMBL618590 | 0.79 | LMNA (0.85) | SMN1; SMN2LMNAHTTKDM4EMMP1 | |
| SCHEMBL21469684 | 0.78 | HTT (0.58) | SMN1; SMN2LMNAHTTKDM4EMMP1 | |
| SCHEMBL17907417 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAHTTMMP1MMP13 | |
| SCHEMBL11143982 | 0.78 | PTGS2 (0.57) | SMN1; SMN2LMNAKDM4EPOLBNPC1 | |
| SCHEMBL7993153 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAHTTKDM4EMMP1 | |
| SCHEMBL13168877 | 0.76 | LMNA (0.51) | SMN1; SMN2LMNAHTTKDM4EMMP1 | |
| SCHEMBL7758697 | 0.76 | ADAMTS4 (0.61) | LMNAKDM4EMMP1MMP13RAB9A | |
| SCHEMBL22874621 | 0.76 | PDE10A (0.52) | SMN1; SMN2KDM4ENPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022225-B2 | Triazole derivative | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20090131438-A1 | Triazole derivative | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2009-05-21 | — | — | US | disclosed |
| US-6228869-B1 | ANTITUMOR, ANTIMETASTASIS, ANTIARTHRITIC, AND WOUND HEALING AGENTS; QUINOLINE AND ISOQUINOLINE DERIVATIVES | AMERICAN CYANAMID COMPANY | 2001-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131438-A1 | Triazole derivative | S1PR3, S1PR1, S1PR2 | SMN1; SMN2 3050/4885LMNA 4808/4885HTT 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.