Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17985011 | 0.98 | KDM4E (0.60) | KDM4EMAPTRAB9ANPC1IDO1 | |
| SCHEMBL2546358 | 0.83 | MAPT (0.70) | KDM4EMAPTRAB9ANPC1HTT | |
| SCHEMBL1733676 | 0.82 | CYP19A1 (0.55) | KDM4EMAPTHSP90AA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7981204 | 0.80 | CTNNB1 (0.60) | KDM4EMAPTRAB9ANPC1IDO1 | |
| SCHEMBL3452459 | 0.80 | RAB9A (0.62) | KDM4EMAPTRAB9ANPC1IDO1 | |
| SCHEMBL3452522 | 0.80 | RAB9A (0.62) | KDM4EMAPTRAB9ANPC1IDO1 | |
| SCHEMBL15942043 | 0.80 | RAB9A (0.54) | KDM4EMAPTRAB9ANPC1IDO1 | |
| SCHEMBL27332292 | 0.79 | NAPRT (0.54) | KDM4EMAPTRAB9ANPC1IDO1 | |
| SCHEMBL11623530 | 0.78 | RAB9A (0.51) | KDM4EMAPTRAB9ANPC1IDO1 | |
| SCHEMBL8804574 | 0.76 | RAB9A (0.50) | KDM4EMAPTRAB9ANPC1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138683-B1 | Organic luminescence device using novel organic boron compounds and process for producing these compounds | CANON KK (JP) | 2005-11-09 | — | — | EP | disclosed |
| US-6461749-B2 | COMPOUND PRODUCING DEVICE CAPABLE OF HIGH LUMINANCE LIGHT EMISSION AT HIGH EFFICIENCY WHILE EXHIBITING LONG LIFE | CANON KABUSHIKI KAISHA (JP) | 2002-10-08 | — | — | US | disclosed |
| US-20020008465-A1 | Novel organic boron compound, process for producing the compound and organic luminescnece device using the compound | CANON KABUSHIKI KAISHA (JP) | 2002-01-24 | — | — | US | disclosed |
| EP-1138683-A2 | Novel organic boron compound, process for producing the compound and organic luminescence device using the compound | CANON KABUSHIKI KAISHA (JP) | 2001-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020008465-A1 | Novel organic boron compound, process for producing the compound and organic luminescnece device using the compound | ARL1, RUVBL1, ARRB1 | KDM4E 1243/4885MAPT 4397/4885RAB9A 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.