Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969242 | 0.88 | TP53 (0.41) | PIN1ALDH1A1TP53KMT2AMAPT | |
| SCHEMBL7980506 | 0.85 | GAA (0.42) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL7981085 | 0.83 | CA12 (0.34) | KMT2AMEN1LMNA | |
| SCHEMBL7969219 | 0.83 | KMT2A (0.34) | TP53OXTRAVPR1APKMKMT2A | |
| SCHEMBL13896765 | 0.74 | MEN1 (0.41) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL7992900 | 0.73 | PTGIR (0.33) | HTT | |
| SCHEMBL7981921 | 0.73 | TSHR (0.40) | MAPTKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL7944573 | 0.72 | TDP1 (0.37) | ALDH1A1TP53MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL7981155 | 0.71 | NR3C2 (0.33) | — | |
| SCHEMBL7980536 | 0.70 | PTGDR2 (0.35) | OXTRAVPR1APKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |