Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982833 | 0.89 | PKM (0.33) | PKMRAB9ANPC1OPRM1OPRD1 | |
| SCHEMBL7982224 | 0.88 | RAB9A (0.34) | PKMRAB9AOPRM1OPRD1HSD11B1 | |
| SCHEMBL7979149 | 0.88 | NPC1 (0.39) | RAB9ANPC1HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL7969219 | 0.87 | KMT2A (0.34) | PKMOPRM1OPRD1OXTRAVPR1A | |
| SCHEMBL7986076 | 0.85 | HDAC1 (0.36) | PTGDR2PKMSLC6A2SLC6A4HDAC1 | |
| SCHEMBL7971749 | 0.85 | KDM4E (0.35) | PTGDR2POLBSLC6A9 | |
| SCHEMBL7969240 | 0.84 | ALDH1A1 (0.36) | RAB9ANPC1HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL7979470 | 0.83 | MAPK1 (0.36) | RAB9ANPC1 | |
| SCHEMBL7980528 | 0.81 | PKM (0.33) | PKMOXTRAVPR1A | |
| SCHEMBL7975471 | 0.81 | ALDH1A1 (0.34) | PKMRAB9AOXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |