Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969219 | 0.87 | KMT2A (0.34) | TDP1TP53L3MBTL1OPRM1OPRD1 | |
| SCHEMBL7986076 | 0.86 | HDAC1 (0.36) | BCHEALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7944575 | 0.84 | ALDH1A1 (0.40) | TDP1TP53MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7969135 | 0.80 | BCHE (0.38) | BCHESLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7945088 | 0.80 | HDAC1 (0.38) | BCHEALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7944087 | 0.79 | BCHE (0.37) | BCHESLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7945107 | 0.76 | POLB (0.36) | MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7947592 | 0.75 | RAB9A (0.36) | BCHESLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL7947140 | 0.75 | PKM (0.37) | CYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL7938360 | 0.74 | POLB (0.36) | MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |