Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981280 | 0.88 | PIN1 (0.40) | TP53MAPTPIN1L3MBTL1LMNA | |
| SCHEMBL7981921 | 0.85 | TSHR (0.40) | MAPTTSHRNPC1RAB9ALMNA | |
| SCHEMBL7979068 | 0.79 | PDE2A (0.40) | TP53MAPTTSHRL3MBTL1ALDH1A1 | |
| SCHEMBL7982554 | 0.76 | SLC6A9 (0.40) | NPC1RAB9A | |
| SCHEMBL13896765 | 0.73 | MEN1 (0.41) | TSHRLMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL7980506 | 0.73 | GAA (0.42) | TSHRLMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL7089442 | 0.73 | HSPA1A (0.45) | TP53NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7945107 | 0.73 | POLB (0.36) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL7944573 | 0.72 | TDP1 (0.37) | TP53MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL7938360 | 0.72 | POLB (0.36) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |