Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.53 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937389 | 0.79 | SSTR4 (0.43) | SLC6A3KCNH2TAAR1SSTR4 | |
| SCHEMBL6940126 | 0.77 | — | — | |
| SCHEMBL23303999 | 0.76 | CHRNB2 (0.42) | SLC6A3KCNH2TAAR1SSTR4 | |
| SCHEMBL30392034 | 0.76 | SLC6A3 (0.36) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL8292968 | 0.75 | SSTR4 (0.45) | SSTR4 | |
| SCHEMBL3742282 | 0.75 | SSTR4 (0.45) | SSTR4 | |
| SCHEMBL28595426 | 0.74 | REN (0.53) | SLC6A3KCNH2SSTR4 | |
| SCHEMBL17697621 | 0.74 | SLC6A3 (0.43) | SLC6A3KCNH2TAAR1SSTR4 | |
| Hydrochloric Acid SCHEMBL4031709 | 0.74 | SSTR4 (0.44) | SSTR4 | |
| SCHEMBL3787216 | 0.73 | SSTR4 (0.38) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011110575-A1 | DERIVATIVES OF 2-[2-(BENZO- OR PYRIDO-) THIAZOLYLAMINO]-6-AMINOPYRIDINE, USEFUL IN THE TREATMENT OF RESPIRATORIC, ALLERGIC OR INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2011-09-15 | — | — | WO | disclosed |