Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 1.00 |
| ▸ | PRKACA | P17612 | 7/20 | 0.76 |
| ▸ | PRKACG | P22612 | 7/20 | 0.76 |
| ▸ | PRKACB | P22694 | 7/20 | 0.76 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980552 | 0.89 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7987325 | 0.86 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7981059 | 0.86 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7981611 | 0.85 | NOX4 (0.77) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7987368 | 0.80 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7987637 | 0.80 | SRC (0.74) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7984187 | 0.76 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7981658 | 0.73 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7987028 | 0.73 | SRC (0.57) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL9367302 | 0.73 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | claimed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |