Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.74 |
| ▸ | PRKACA | P17612 | 5/20 | 0.73 |
| ▸ | PRKACG | P22612 | 5/20 | 0.73 |
| ▸ | PRKACB | P22694 | 5/20 | 0.73 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980552 | 0.85 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7983999 | 0.85 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7987368 | 0.81 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7981604 | 0.80 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7984187 | 0.77 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7980495 | 0.70 | SRC (0.49) | SRCPRKACAPRKACGPRKACBABCB11 | |
| SCHEMBL9367302 | 0.68 | SRC (1.00) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7981609 | 0.67 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7983884 | 0.67 | SRC (0.67) | SRCPRKACAPRKACGPRKACBABCB11 | |
| SCHEMBL7981658 | 0.66 | SRC (1.00) | SRCPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |