Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 5/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.40 |
| ▸ | DHODH | Q02127 | 6/20 | 0.40 |
| ▸ | RORC | P51449 | 5/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807714 | 0.79 | ITK (0.46) | ITKLCKSSTR5DHODHRORC | |
| SCHEMBL2370393 | 0.72 | ITK (0.47) | ITKLCKSSTR5RAB9AAURKB | |
| SCHEMBL2370389 | 0.72 | ITK (0.47) | ITKLCKSSTR5RAB9AAURKB | |
| SCHEMBL2398982 | 0.70 | ITK (0.57) | ITKLCKSSTR5DHODHRORC | |
| SCHEMBL2398991 | 0.70 | ITK (0.57) | ITKLCKSSTR5DHODHRORC | |
| SCHEMBL807541 | 0.70 | ITK (0.55) | ITKLCKSSTR5DHODHRORC | |
| SCHEMBL807721 | 0.70 | KMT2A (0.49) | ITKLCKRAB9AAURKBNPC1 | |
| SCHEMBL2379918 | 0.70 | ITK (0.45) | ITKLCKAURKBSMN1; SMN2HTT | |
| SCHEMBL2379924 | 0.70 | ITK (0.45) | ITKLCKAURKBSMN1; SMN2HTT | |
| SCHEMBL807926 | 0.69 | ITK (0.59) | ITKLCKSSTR5DHODHRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |